[CAS NO. 1004551-40-9] BMS-593214

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PRODUCTS SPECIFICATIONS [1004551-40-9]

Catalog

HY-114511

Brand

MCE

CAS

1004551-40-9

DESCRIPTION [1004551-40-9]

Overview

MDL	-
Molecular Weight	505.56
Molecular Formula	C31H27N3O4
SMILES	O=C(O)C1=CC=C(C=C1)C2=CC(O)=C(C=C2[C@@H]3NC4=C([C@@]5([C@]3(CC6=C5C=CC=C6)[H])[H])C=C(C=C4)C(N)=N)OC

For research use only. We do not sell to patients.

Summary

BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT) ^[1] .

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References

[1] Wong PC, et al. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thromb Haemost. 2010 Aug;104(2):261-9.