[CAS NO. 1011301-27-1] Tenovin-3

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PRODUCTS SPECIFICATIONS [1011301-27-1]

Catalog

HY-19339

Brand

MCE

CAS

1011301-27-1

DESCRIPTION [1011301-27-1]

Overview

MDL	MFCD25976437
Molecular Weight	327.44
Molecular Formula	C18H21N3OS
SMILES	O=C(NC(NC1=CC=C(N)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2

For research use only. We do not sell to patients.

Summary

Tenovin-3 is a p53 activator ^[1] ^[2] .

In Vitro

Tenovin-3 downregulates both P-FAK and P-Src ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 31 mg/mL ( 94.67 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0540 mL	15.2700 mL	30.5399 mL
5 mM	0.6108 mL	3.0540 mL	6.1080 mL
10 mM	0.3054 mL	1.5270 mL	3.0540 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (7.63 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (7.63 mM); Clear solution

* All of the co-solvents are available by MCE.