[CAS NO. 101328-85-2] OR-1855

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PRODUCTS SPECIFICATIONS [101328-85-2]

Catalog

HY-W050000

Brand

MCE

CAS

101328-85-2

DESCRIPTION [101328-85-2]

Overview

MDL	MFCD09032921
Molecular Weight	203.24
Molecular Formula	C11H13N3O
SMILES	O=C1C[C@@H](C)C(C2=CC=C(N)C=C2)=NN1

For research use only. We do not sell to patients.

Summary

OR-1855, an active metabolite of Levosimendan, has effect on human myometrial contractility. Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure ^[1] ^[2] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 492.03 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9203 mL	24.6015 mL	49.2029 mL
5 mM	0.9841 mL	4.9203 mL	9.8406 mL
10 mM	0.4920 mL	2.4601 mL	4.9203 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (12.30 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (12.30 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

3(2H)-Pyridazinone, 6-(4-aminophenyl)-4,5-dihydro-5-methyl-, (5R)-

3(2H)-Pyridazinone, 6-(4-aminophenyl)-4,5-dihydro-5-methyl-, (R)-

(5R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

OR 1855

(R)-6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

(5R)-6-(4-Aminophenyl)-5-methyl-2,3,4,5-tetrahydropyridazin-3-one

(R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

(4R)-3-(4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one