[CAS NO. 104561-41-3]  EC23

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PRODUCTS SPECIFICATIONS [104561-41-3]

Catalog
HY-12309
Brand
MCE
CAS
104561-41-3

DESCRIPTION [104561-41-3]

Overview

MDLMFCD18086921
Molecular Weight332.44
Molecular FormulaC23H24O2
SMILESO=C(O)C1=CC=C(C#CC2=CC=C3C(C)(C)CCC(C)(C)C3=C2)C=C1

For research use only. We do not sell to patients.

Summary

EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation [1] .


In Vitro

EC23 (AGN 190205) induces neural differentiation accompanying by elevated levels of stathmin and profilin-1. EC23 induces the expression of known cellular retinoid binding proteins in the TERA2.cl.SP12 cell line [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 376.01 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0081 mL 15.0403 mL 30.0806 mL
5 mM 0.6016 mL 3.0081 mL 6.0161 mL
10 mM 0.3008 mL 1.5040 mL 3.0081 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.08 mg/mL (6.26 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: 2.08 mg/mL (6.26 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.26 mM); Clear solution

* All of the co-solvents are available by MCE.