[CAS NO. 112-86-7] Erucic acid
PRODUCTS SPECIFICATIONS [112-86-7]
DESCRIPTION [112-86-7]
Overview
| MDL | MFCD00063188 |
|---|---|
| Molecular Weight | 338.57 |
| Molecular Formula | C22H42O2 |
| SMILES | CCCCCCCC/C=C\CCCCCCCCCCCC(O)=O |
Summary
Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia [1] .
IC50 & Target
|
Human Endogenous Metabolite |
In Vivo
Erucic acid (oral administration; 3 mg/kg) enhances the phosphorylation level of PI3K, PKCζ, ERK, CREB and Akt in the hippocampus compared with that in the vehicle-treated control group
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Normal naïve mice [1] |
| Dosage: | 3 mg/kg |
| Administration: | Oral administration; 3 mg/kg |
| Result: | Enhanced the phosphorylation level of PI3K, PKCζ, ERK, CREB and Akt in the hippocampus. |
Appearance
<28°C Solid,>32°C Liquid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Pure form | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 295.36 mM )
H 2 O : 1 mg/mL ( 2.95 mM ; ultrasonic and warming and heat to 80°C)
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.9536 mL | 14.7680 mL | 29.5360 mL |
| 5 mM | 0.5907 mL | 2.9536 mL | 5.9072 mL |
| 10 mM | 0.2954 mL | 1.4768 mL | 2.9536 mL |
Synonyms