[CAS NO. 113085-62-4] 7-Methoxyrosmanol

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PRODUCTS SPECIFICATIONS [113085-62-4]

Catalog

HY-111896

Brand

MCE

CAS

113085-62-4

DESCRIPTION [113085-62-4]

Overview

MDL	-
Molecular Weight	360.44
Molecular Formula	C21H28O5
SMILES	O=C1[C@](C(C2=CC(C(C)C)=C3O)=C3O)(CCCC(C)4C)[C@@]4([H])[C@@H]([C@H]2OC)O1

For research use only. We do not sell to patients.

Summary

7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 277.44 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7744 mL	13.8719 mL	27.7439 mL
5 mM	0.5549 mL	2.7744 mL	5.5488 mL
10 mM	0.2774 mL	1.3872 mL	2.7744 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 2.5 mg/mL (6.94 mM); Clear solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (6.94 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Young Sook Yun, et al. Phenolic Diterpenes From Rosemary Suppress cAMP Responsiveness of Gluconeogenic Gene Promoters. Phytother Res. 2013 Jun;27(6):906-10.

Synonyms

2H-10,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-9-methoxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10S,10aS)-

2H-10,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-9-methoxy-1,1-dimethyl-7-(1-methylethyl)-, [4aR-(4aα,9β,10α,10aβ)]-

(4aR,9S,10S,10aS)-1,3,4,9,10,10a-Hexahydro-5,6-dihydroxy-9-methoxy-1,1-dimethyl-7-(1-methylethyl)-2H-10,4a-(epoxymethano)phenanthren-12-one

7-Methoxyrosamanol

7-o-Methylrosmanol

7-Methoxyrosmanol

7α-Methoxyrosmanol