[CAS NO. 1146-99-2] Chlorindione

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PRODUCTS SPECIFICATIONS [1146-99-2]

Catalog

HY-B0918

Brand

MCE

CAS

1146-99-2

DESCRIPTION [1146-99-2]

Overview

MDL	MFCD00239203
Molecular Weight	256.68
Molecular Formula	C15H9ClO2
SMILES	O=C1C(C2=CC=C(Cl)C=C2)C(C3=C1C=CC=C3)=O

For research use only. We do not sell to patients.

Summary

Chlorindione (Chlophenadione) is a potent anticoagulant. Chlorindione also is a vitamin K1 antagonist ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 389.59 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8959 mL	19.4795 mL	38.9590 mL
5 mM	0.7792 mL	3.8959 mL	7.7918 mL
10 mM	0.3896 mL	1.9480 mL	3.8959 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (9.74 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (9.74 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (9.74 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Danek A, et, al. Studies on absorption and elimination of drugs. II. The kinetics of distribution and elimination of clorindion in the rabbit. Pol J Pharmacol Pharm. May-Jun 1973;25(3):307-11.

Synonyms

1H-Indene-1,3(2H)-dione, 2-(4-chlorophenyl)-

1,3-Indandione, 2-(p-chlorophenyl)-

2-(4-Chlorophenyl)-1H-indene-1,3(2H)-dione

G 25766

Chlorphenindione

Indaliton

Chlorindione

Indalitan

2-(p-Chlorophenyl)-1,3-indandione

Clorindione

2-(4-Chlorophenyl)-1,3-indandione

M.G. 2552

Chlophenadione

Chlorphenadione

Chlorathrombon

Chlorindion

2-(4-Chloro-phenyl)-indane-1,3-dione

2-(4-Chlorophenyl)indene-1,3-dione

2-(4-Chlorophenyl)-2,3-dihydro-1H-indene-1,3-dione