[CAS NO. 115453-99-1] CB-7921220
PRODUCTS SPECIFICATIONS [115453-99-1]
DESCRIPTION [115453-99-1]
Overview
| MDL | MFCD05999206 |
|---|---|
| Molecular Weight | 240.26 |
| Molecular Formula | C14H12N2O2 |
| SMILES | O=C(C1=NC(/C=C/C2=CC=C(N)C=C2)=CC=C1)O |
Summary
CB-7921220 is an adenylate cyclase inhibitor.
In Vitro
CB-7921220 shows a degree of isoform selectivity for adenylate cyclase (AC) 1, but cannot distinguish between AC1 and AC6. CB-7921220 has a more consistent predicted binding position in the two virtual docking screens, and has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6 [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 50 mg/mL ( 208.11 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.1622 mL | 20.8108 mL | 41.6216 mL |
| 5 mM | 0.8324 mL | 4.1622 mL | 8.3243 mL |
| 10 mM | 0.4162 mL | 2.0811 mL | 4.1622 mL |
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1.