[CAS NO. 118-10-5] Cinchonine

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PRODUCTS SPECIFICATIONS [118-10-5]

Catalog

HY-Y0152

Brand

MCE

CAS

118-10-5

DESCRIPTION [118-10-5]

Overview

MDL	MFCD00064372
Molecular Weight	294.39
Molecular Formula	C19H22N2O
SMILES	O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Front Cell Infect Microbiol. 14 June 2022.

Summary

Cinchonine is a natural compound present in Cinchona bark. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 4.76 mg/mL ( 16.17 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3969 mL	16.9843 mL	33.9685 mL
5 mM	0.6794 mL	3.3969 mL	6.7937 mL
10 mM	0.3397 mL	1.6984 mL	3.3969 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Jin ZL, et al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.

Synonyms

Cinchonan-9-ol, (9S)-

Cinchonine

(9S)-Cinchonan-9-ol

d-Cinchonine

(+)-Cinchonine

(8R,9S)-Cinchonine

NSC 6176