[CAS NO. 1184940-46-2] EMD638683S-Form

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PRODUCTS SPECIFICATIONS [1184940-46-2]

Catalog

HY-15193B

Brand

MCE

CAS

1184940-46-2

DESCRIPTION [1184940-46-2]

Overview

MDL	-
Molecular Weight	364.34
Molecular Formula	C18H18F2N2O4
SMILES	CC1=C(CC)C(C(NNC([C@@H](O)C2=CC(F)=CC(F)=C2)=O)=O)=CC=C1O

For research use only. We do not sell to patients.

Summary

EMD638683 S-Form is the S-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC ₅₀ of 3 μM.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL ( 274.47 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7447 mL	13.7234 mL	27.4469 mL
5 mM	0.5489 mL	2.7447 mL	5.4894 mL
10 mM	0.2745 mL	1.3723 mL	2.7447 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.75 mg/mL (7.55 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.75 mg/mL (7.55 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.75 mg/mL (7.55 mM); Clear solution

* All of the co-solvents are available by MCE.