[CAS NO. 1184940-47-3] EMD638683R-Form

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PRODUCTS SPECIFICATIONS [1184940-47-3]

Catalog

HY-15193A

Brand

MCE

CAS

1184940-47-3

MDL	-
Molecular Weight	364.34
Molecular Formula	C18H18F2N2O4
SMILES	CC1=C(CC)C(C(NNC([C@H](O)C2=CC(F)=CC(F)=C2)=O)=O)=CC=C1O

For research use only. We do not sell to patients.

EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC ₅₀ of 3 μM.

SGK1 ^[1]

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 66.67 mg/mL ( 182.99 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 3.33 mg/mL (9.14 mM); Clear solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 3.33 mg/mL (9.14 mM); Clear solution; Need ultrasonic
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: 3.33 mg/mL (9.14 mM); Clear solution; Need ultrasonic

* All of the co-solvents are available by MCE.