[CAS NO. 119152-50-0] Glychionide A

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PRODUCTS SPECIFICATIONS [119152-50-0]

Catalog

HY-N8034

Brand

MCE

CAS

119152-50-0

DESCRIPTION [119152-50-0]

Overview

MDL	-
Molecular Weight	446.36
Molecular Formula	C21H18O11
SMILES	O=C1C(C(OC(C2=CC=CC=C2)=C1)=C3O)=C(C=C3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)O

For research use only. We do not sell to patients.

Summary

Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra . Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer ^[1] ^[2] .

In Vitro

Glychionide A (3.12-100 μM) significantly inhibits the proliferation of the PANC-1 pancreatic cancer cells, with an IC ₅₀ of 14 μM ^[1] .
Glychionide A (7-28 μM) induces both autophagy and apoptosis in pancreatic cancer cells ^[1] .
Glychionide A (7-28 μM) causes G2/M arrest of PANC-1 pancreatic cancer cells ^[1] .
Glychionide A (7-28 μM) causes generation of ROS in PANC-1 cells ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)