[CAS NO. 121058-88-6]  Ac-rC Phosphoramidite

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PRODUCTS SPECIFICATIONS [121058-88-6]

Catalog
HY-W042357
Brand
MCE
CAS
121058-88-6

DESCRIPTION [121058-88-6]

Overview

MDLMFCD09842111
Molecular Weight902.10
Molecular FormulaC47H64N5O9PSi
SMILESCOC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N5C(N=C(NC(C)=O)C=C5)=O)O4

For research use only. We do not sell to patients.

Summary

Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA) [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 110.85 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1085 mL 5.5426 mL 11.0852 mL
5 mM 0.2217 mL 1.1085 mL 2.2170 mL
10 mM 0.1109 mL 0.5543 mL 1.1085 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.5 mg/mL (2.77 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.77 mM); Clear solution

* All of the co-solvents are available by MCE.