[CAS NO. 123-08-0] p-Hydroxybenzaldehyde
PRODUCTS SPECIFICATIONS [123-08-0]
DESCRIPTION [123-08-0]
Overview
| MDL | MFCD00006939 |
|---|---|
| Molecular Weight | 122.12 |
| Molecular Formula | C7H6O2 |
| SMILES | O=CC1=CC=C(O)C=C1 |
Summary
p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABA A receptor of the α 1 β 2 γ 2 S subtype at high concentrations.
IC50 & Target
|
Human Endogenous Metabolite |
In Vitro
p-Hydroxybenzaldehyde (4-hydroxybenzaldehyde) is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABA A receptor of the α 1 β 2 γ 2 S subtype at high concentrations. p-Hydroxybenzaldehyde (101.7 μM) significantly reduces the GABA-induced chloride current of GABA A receptors expressed on Xenopus oocytes [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL ( 818.87 mM ; Need ultrasonic)
H 2 O : 10 mg/mL ( 81.89 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 8.1887 mL | 40.9433 mL | 81.8867 mL |
| 5 mM | 1.6377 mL | 8.1887 mL | 16.3773 mL |
| 10 mM | 0.8189 mL | 4.0943 mL | 8.1887 mL |
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1.
Add each solvent one by one: PBS
Solubility: 14.29 mg/mL (117.02 mM); Clear solution; Need ultrasonic
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2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (20.47 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (20.47 mM); Clear solution
Synonyms