[CAS NO. 124-76-5]  Isoborneol

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PRODUCTS SPECIFICATIONS [124-76-5]

Catalog
HY-N2004
Brand
MCE
CAS
124-76-5

DESCRIPTION [124-76-5]

Overview

MDLMFCD00074821
Molecular Weight154.25
Molecular FormulaC10H18O
SMILESC[C@@]([C@@H]1O)(CC[C@@H]2C1)C2(C)C

For research use only. We do not sell to patients.

Summary

Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1) [1] [2] .


IC50 & Target

HSV-1


In Vitro

Isoborneol ((±)-Isoborneol) protects against 6-OHDA-induced increases in caspase-3 activity and cytochrome C translocation into the cytosol from mitochondria. Isoborneol prevents 6-OHDA from decreasing the Bax/Bcl-2 ratio [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 648.30 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4830 mL 32.4149 mL 64.8298 mL
5 mM 1.2966 mL 6.4830 mL 12.9660 mL
10 mM 0.6483 mL 3.2415 mL 6.4830 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (16.21 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (16.21 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (16.21 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, (1R,2R,4R)-rel-
Isoborneol
Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, exo-
rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol
Isobornyl alcohol
exo-2-Hydroxy-1,7,7-trimethylnorbornane
2-exo-Bornyl alcohol
(±)-Isoborneol
dl-Isoborneol
DL-Isoborneol
NSC 26350