[CAS NO. 1253186-46-7] GSK-5503A

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PRODUCTS SPECIFICATIONS [1253186-46-7]

Catalog

HY-103071

Brand

MCE

CAS

1253186-46-7

DESCRIPTION [1253186-46-7]

Overview

MDL	-
Molecular Weight	405.40
Molecular Formula	C23H17F2N3O2
SMILES	O=C(NC1=NN(CC2=CC=CC=C2OC3=CC=CC=C3)C=C1)C4=C(F)C=CC=C4F

For research use only. We do not sell to patients.

Summary

GSK-5503A is a calcium-release activated calcium ( CRAC ) channel blocker. GSK-5503A effectively inhibits stromal interaction molecule 1 (STIM1) mediated Orai1 and Orai3 currents in vitro. GSK-5503A can be used for the research of asthma and allergic disorders ^[1] .

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Derler I, et al. The action of selective CRAC channel blockers is affected by the Orai pore geometry. Cell Calcium. 2013 Feb;53(2):139-51.