[CAS NO. 1259-86-5] (+)-Glaucarubinone

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PRODUCTS SPECIFICATIONS [1259-86-5]

Catalog

HY-N10926

Brand

MCE

CAS

1259-86-5

DESCRIPTION [1259-86-5]

Overview

MDL	-
Molecular Weight	494.53
Molecular Formula	C25H34O10
SMILES	C[C@@]12[C@]3([H])[C@]45[C@@]([C@H]([C@H]([C@@]3(OC5)O)O)C)([H])[C@H](C(O[C@]4([H])C[C@@]1([H])C(C)=CC([C@H]2O)=O)=O)OC([C@@](C)(O)CC)=O

For research use only. We do not sell to patients.

Summary

(+)-Glaucarubinone is a potent AP-1 (activator protein-1) inhibitor with an EC ₅₀ value of 0.13 µM. (+)-Glaucarubinone shows noncytotoxic ^[1] .

IC50 & Target

EC ₅₀ : 0.13 µM (AP-1) ^[1]

Source

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Diyabalanage T, et al. Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4397-9.