[CAS NO. 1402931-71-8] eIF4A3-IN-9
PRODUCTS SPECIFICATIONS [1402931-71-8]
DESCRIPTION [1402931-71-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 505.52 |
| Molecular Formula | C28H27NO8 |
| SMILES | O[C@]12[C@](OC3=CC(C(N)=O)=CC(OC)=C32)(C4=CC=C(C=C4)OC)[C@H](C5=CC=CC=C5)[C@H]([C@H]1O)C(OC)=O |
Summary
eIF4A3-IN-9 (compound 57) is a silvestrol (HY-13251) analogue. eIF4A3-IN-9 interferes the assembling of eIF4F translation complex with EC 50 s of 29, 450 and 80 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-9 can be used for the research of human cancer pathogenesis [1] .
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.