[CAS NO. 1402931-75-2] eIF4A3-IN-17
PRODUCTS SPECIFICATIONS [1402931-75-2]
DESCRIPTION [1402931-75-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 487.50 |
| Molecular Formula | C28H25NO7 |
| SMILES | COC1=CC=C([C@@]23OC4=CC(C#N)=CC(OC)=C4[C@]2(O)[C@@H]([C@@H]([C@H]3C5=CC=CC=C5)C(OC)=O)O)C=C1 |
Summary
eIF4A3-IN-17 (compound 61) is a silvestrol (HY-13251) analogue. eIF4A3-IN-17 interferes the assembling of eIF4F translation complex with EC 50 s of 0.9, 15 and 1.8 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-17 can be used for the research of human cancer pathogenesis [1] .
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.