[CAS NO. 1402931-76-3] eIF4A3-IN-12
PRODUCTS SPECIFICATIONS [1402931-76-3]
DESCRIPTION [1402931-76-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 496.94 |
| Molecular Formula | C27H25ClO7 |
| SMILES | COC1=CC=C([C@@]23OC4=CC(Cl)=CC(OC)=C4[C@]2(O)[C@@H]([C@@H]([C@H]3C5=CC=CC=C5)C(OC)=O)O)C=C1 |
Summary
eIF4A3-IN-12 (compound 62) is a silvestrol (HY-13251) analogue. eIF4A3-IN-12 interferes the assembling of eIF4F translation complex with EC 50 s of 4, 70 and 5 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-12 can be used for the research of human cancer pathogenesis [1] .
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.