[CAS NO. 1429028-96-5] MM41

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PRODUCTS SPECIFICATIONS [1429028-96-5]

Catalog

HY-16967

Brand

MCE

CAS

1429028-96-5

DESCRIPTION [1429028-96-5]

Overview

MDL	-
Molecular Weight	831.06
Molecular Formula	C44H66N10O6
SMILES	O=C1C2=CC(NCCCN3CCN(CC3)C)=C4C(N(CCCN5CCOCC5)C(C6=CC(NCCCN7CCN(CC7)C)=C(C2=C64)C(N1CCCN8CCOCC8)=O)=O)=O

For research use only. We do not sell to patients.

Summary

MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC ₅₀ value of <10 nM ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL ( 40.11 mM ; ultrasonic and adjust pH to 8 with HCl)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2033 mL	6.0164 mL	12.0328 mL
5 mM	0.2407 mL	1.2033 mL	2.4066 mL
10 mM	0.1203 mL	0.6016 mL	1.2033 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Marialuisa Micco, et al. Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells. J Med Chem