[CAS NO. 14432-09-8] 1-Deazaadenosine

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PRODUCTS SPECIFICATIONS [14432-09-8]

Catalog

HY-103159

Brand

MCE

CAS

14432-09-8

DESCRIPTION [14432-09-8]

Overview

MDL	-
Molecular Weight	266.25
Molecular Formula	C11H14N4O4
SMILES	NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H](CO)O3)O)O)C=N2)=NC=C1

For research use only. We do not sell to patients.

Summary

1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a K _i value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders ^[1] ^[2] .

In Vitro

1-Deazaadenosine shows good activity in vitro as inhibitor of HeLa, KB, P388, and L1210 leukemia cell line growth, with ID ₅₀ values ranging from 0.34 μM (KB) to 1.8 μM (P388) ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month