[CAS NO. 1450894-16-2] Kinetin triphosphate
PRODUCTS SPECIFICATIONS [1450894-16-2]
DESCRIPTION [1450894-16-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 587.27 |
| Molecular Formula | C15H20N5O14P3 |
| SMILES | O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(NCC4=CC=CO4)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O |
Summary
Kinetin triphosphate(6-Fu-ATP; KTP) is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate can be used in Parkinson's disease research [1] .
In Vitro
Kinetin triphosphate can act as a phosphate donor for PINK1 to recognize the T257 autophosphorylation site, and can restore the catalytic activity of PINK1 G309D to close to WT levels in HeLa cells in vitro
[1]
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MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.