[CAS NO. 1462949-64-9]  ALKkinaseinhibitor-1

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PRODUCTS SPECIFICATIONS [1462949-64-9]

Catalog
HY-19990
Brand
MCE
CAS
1462949-64-9

DESCRIPTION [1462949-64-9]

Overview

MDL-
Molecular Weight537.65
Molecular FormulaC28H32FN5O3S
SMILESCN(CC1)CCN1C2=CC=C(NC3=NC=C4C(C(C5=C(OC)C=CC(F)=C5)=C(CO)S4)=N3)C(OC(C)C)=C2

For research use only. We do not sell to patients.

Summary

ALK kinase inhibitor-1 is an anaplastic lymphoma kinase (ALK) inhibitor extracted from patent US20130261106A1 compound I-202 [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 185.99 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8599 mL 9.2997 mL 18.5995 mL
5 mM 0.3720 mL 1.8599 mL 3.7199 mL
10 mM 0.1860 mL 0.9300 mL 1.8599 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (4.65 mM); Clear solution

* All of the co-solvents are available by MCE.