[CAS NO. 14660-91-4] Neoxanthin

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PRODUCTS SPECIFICATIONS [14660-91-4]

Catalog

HY-N7523

Brand

MCE

CAS

14660-91-4

DESCRIPTION [14660-91-4]

Overview

MDL	-
Molecular Weight	600.87
Molecular Formula	C40H56O4
SMILES	CC(/C=C/[C@](O1)(C(C)(C2)C)[C@]1(C[C@H]2O)C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=[C@@]=C([C@](O)(C3)C)C(C)(C[C@@H]3O)C

For research use only. We do not sell to patients.

Summary

Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions ^[1] ^[2] .

In Vitro

Neoxanthin (20 μM; 72 h) treatment significantly reduces cell viability to 10.9% for PC-3 cells, 15.0% for DU 145 cells, and nearly zero for LNCaP cells, respectively ^[1] .
Neoxanthin strongly inhibits cell growth by suppressing DNA synthesis in C3H10T1/2 cells ^[1] .
In photosynthetic organisms, Neoxanthin is the essential component of both the photosystem I (PSI) and photosystem II (PSII) reaction centers of oxygenic photosynthetic apparatus ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The gastrointestinal metabolism of Neoxanthin in mice is investigated. Two hours after the oral administration of Neoxanthin (40 nmol/mouse), Neoxanthin is found in the plasma and livers of mice. The concentrations of Neoxanthin is 13.6-9.0 nM in plasma, and 7.3 3.6 pmol/g in liver, respectively. (R/S)-Neochrome is also found in the small intestinal contents of Neoxanthin-administered mice ^[3] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

References

Synonyms

β,β-Carotene-3,3′,5(6H)-triol, 6,7-didehydro-5′,6′-epoxy-5′,6′-dihydro-, (3S,3′S,5R,5′R,6R,6′S,9′-cis)-

β-Carotene, 6,7-didehydro-5′,6′-epoxy-5,5′,6,6′-tetrahydro-3,3′,5-trihydroxy-, (3S,3′S,5′R,6′S)-

β,β-Carotene, 6,7-didehydro-5′,6′-epoxy-5,5′,6,6′-tetrahydro-3,3′,5-trihydroxy-, (3S,3′S,5R,5′R,6R,6′S,9′-cis)-

Foliaxanthin

(3S,3′S,5R,5′R,6R,6′S,9′-cis)-6,7-Didehydro-5′,6′-epoxy-5′,6′-dihydro-β,β-carotene-3,3′,5(6H)-triol

Neoxanthin

9-cis-Neoxanthin

Neoxanthine

cis-Neoxanthin

(9′Z)-Neoxanthin

9′Z-(6R)-neoxanthin

9′-cis-Neoxanthin