[CAS NO. 148672-09-7] Estrone O-sulfamate
PRODUCTS SPECIFICATIONS [148672-09-7]
DESCRIPTION [148672-09-7]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 349.44 |
| Molecular Formula | C18H23NO4S |
| SMILES | C[C@@]12[C@](CCC2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OS(N)(=O)=O)C=C4CC3 |
Summary
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC 50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer [1] .
In Vitro
Estrone O-sulfamate (Estrone 3-O-sulfamate) has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC 50 values of 18 nM and 0.83 nM, respectively [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.