[CAS NO. 1491150-77-6] Syk-IN-1

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PRODUCTS SPECIFICATIONS [1491150-77-6]

Catalog

HY-12657

Brand

MCE

CAS

1491150-77-6

MDL	-
Molecular Weight	366.42
Molecular Formula	C18H22N8O
SMILES	NC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O

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Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC ₅₀ of 35 nM ^[1] .

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 100 mg/mL ( 272.91 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 5 mg/mL (13.65 mM); Clear solution

* All of the co-solvents are available by MCE.