[CAS NO. 1496997-41-1] Thalidomide-5,6-F
PRODUCTS SPECIFICATIONS [1496997-41-1]
DESCRIPTION [1496997-41-1]
Overview
| MDL | MFCD32853274 |
|---|---|
| Molecular Weight | 294.21 |
| Molecular Formula | C13H8F2N2O4 |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(F)C(F)=C3)=O |
Summary
IC50 & Target
|
Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 33.33 mg/mL ( 113.29 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.3989 mL | 16.9947 mL | 33.9893 mL |
| 5 mM | 0.6798 mL | 3.3989 mL | 6.7979 mL |
| 10 mM | 0.3399 mL | 1.6995 mL | 3.3989 mL |