[CAS NO. 1507367-37-4] FINDY

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PRODUCTS SPECIFICATIONS [1507367-37-4]

Catalog

HY-152183

Brand

MCE

CAS

1507367-37-4

DESCRIPTION [1507367-37-4]

Overview

MDL	-
Molecular Weight	347.53
Molecular Formula	C16H17NO2S2Si
SMILES	C[Si](C)(C)C#CC1=C(C=CC(/C=C2SC(NC\2=O)=S)=C1)OC

For research use only. We do not sell to patients.

Summary

FINDY is a folding intermediate-selective inhibitor of DYRK1A . FINDY can inhibit Ser97 autophosphorylation with an IC ₅₀ value of 35 μM. FINDY can be used for the research of neurological disorder ^[1] .

IC50 & Target

IC50: 35 μM (Ser97 autophosphorylation) ^[1]

In Vitro

FINDY (Compound 1) inhibits Ser97 autophosphorylation with an IC ₅₀ value of 35 μM ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Yuka Miyazaki, et al. Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. Eur J Med Chem. 2022 Jan 5;227:113948.