[CAS NO. 1571076-26-0] Tenofoviramibufenamide

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PRODUCTS SPECIFICATIONS [1571076-26-0]

Catalog

HY-137453

Brand

MCE

CAS

1571076-26-0

DESCRIPTION [1571076-26-0]

Overview

MDL	-
Molecular Weight	490.49
Molecular Formula	C22H31N6O5P
SMILES	C[C@@H](OC[P@](OC1=CC=CC=C1)(NC(C)(C)C(OC(C)C)=O)=O)CN2C3=NC=NC(N)=C3N=C2

For research use only. We do not sell to patients.

Summary

Tenofovir amibufenamide (HS-10234), a Tenofovir prodrug, is an orally active antiviral agent. Tenofovir amibufenamide inhibits HBV , and can be used for chronic hepatitis B (CHB) study ^[1] ^[2] .

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT05398393	Wuhan Union Hospital, China	Hepatitis B, Chronic\|Lipid Disorder	January 1, 2022	Not Applicable
NCT04477096	Jiangsu Hansoh Pharmaceutical Co., Ltd.	Healthy Subjects	August 3, 2020	Phase 1
NCT05382351	Sun Yat-sen University	Chronic Hepatitis B Virus Infection	May 10, 2022	Phase 2
NCT03903796	Jiangsu Hansoh Pharmaceutical Co., Ltd.	Chronic HBV Infection	August 16, 2018	Phase 3

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL ( 407.76 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0388 mL	10.1939 mL	20.3878 mL
5 mM	0.4078 mL	2.0388 mL	4.0776 mL
10 mM	0.2039 mL	1.0194 mL	2.0388 mL

* Please refer to the solubility information to select the appropriate solvent.