[CAS NO. 161099-37-2] Glicoricone
PRODUCTS SPECIFICATIONS [161099-37-2]
DESCRIPTION [161099-37-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 368.38 |
| Molecular Formula | C21H20O6 |
| SMILES | O=C1C(C2=C(O)C=C(O)C(C/C=C(C)\C)=C2OC)=COC3=CC(O)=CC=C13 |
Summary
Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO) , with an IC 50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity [1] [2] .
IC50 & Target
IC50: 140 μM (monoamine oxidase) [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
References
- [1] Hatano T, et, al. Phenolic constituents of licorice. III. Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase. Chem Pharm Bull (Tokyo). 1991 May;39(5):1238-43.
- [2] Boonmuen N, et, al. Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids. 2016 Jan;105:42-9.
Synonyms