[CAS NO. 1621-56-3]  7-Methoxyisoflavone

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PRODUCTS SPECIFICATIONS [1621-56-3]

Catalog
HY-N6631
Brand
MCE
CAS
1621-56-3

DESCRIPTION [1621-56-3]

Overview

MDLMFCD00181416
Molecular Weight252.26
Molecular FormulaC16H12O3
SMILESO=C1C(C2=CC=CC=C2)=COC3=CC(OC)=CC=C13

For research use only. We do not sell to patients.


Summary

7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase ( AMPK ).


IC50 & Target

AMPK [1]


In Vitro

7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). When serum-starved cells are treated with 10 % FBS in the presence of 7-methoxyisoflavone, the serum-induced decrease in AMPK phosphorylation is prevented [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 99.10 mM ; Need ultrasonic)

H 2 O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9642 mL 19.8208 mL 39.6416 mL
5 mM 0.7928 mL 3.9642 mL 7.9283 mL
10 mM 0.3964 mL 1.9821 mL 3.9642 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (9.91 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.91 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

4H-1-Benzopyran-4-one, 7-methoxy-3-phenyl-
Isoflavone, 7-methoxy-
7-Methoxy-3-phenyl-4H-1-benzopyran-4-one
7-Methoxyisoflavone
7-Methoxy-3-phenyl-4H-chromen-4-one