[CAS NO. 1621523-07-6] THZ1-R
PRODUCTS SPECIFICATIONS [1621523-07-6]
DESCRIPTION [1621523-07-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 568.07 |
| Molecular Formula | C31H30ClN7O2 |
| SMILES | ClC1=CN=C(NC2=CC(NC(C3=CC=C(NC(CCCN(C)C)=O)C=C3)=O)=CC=C2)N=C1C4=CNC5=CC=CC=C54 |
3 Publications Citing Use of MCE
Summary
IC50 & Target
|
CDK7 146 nM (IC 50 ) |
In Vitro
THZ1-R shows lower affinity at CDK7 than THZ1, with IC 50 of 146 nM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 176.03 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.7603 mL | 8.8017 mL | 17.6035 mL |
| 5 mM | 0.3521 mL | 1.7603 mL | 3.5207 mL |
| 10 mM | 0.1760 mL | 0.8802 mL | 1.7603 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (4.40 mM); Clear solution