[CAS NO. 1634620-63-5] Aprutumab

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PRODUCTS SPECIFICATIONS [1634620-63-5]

Catalog

HY-P99007

Brand

MCE

CAS

1634620-63-5

DESCRIPTION [1634620-63-5]

Overview

MDL	-
Molecular Weight	-
Molecular Formula	-
SMILES	[Aprutumab]

For research use only. We do not sell to patients.

Summary

Aprutumab (BAY 1179470) is a fully human FGFR2 monoclonal antibody, which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc. Aprutumab has the potential for solid tumors research ^[1] .

IC50 & Target

FGFR2-IIIb

FGFR2-IIIc

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT01881217	Bayer	Neoplasms	June 28, 2013	Phase 1

Appearance

Liquid

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Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Anette Sommer, et al. Preclinical Efficacy of the Auristatin-Based Antibody–Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors. Cancer Res (2016) 76 (21): 6331–6339.