[CAS NO. 1644248-18-9]  BMS-911172

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PRODUCTS SPECIFICATIONS [1644248-18-9]

Catalog
HY-115868
Brand
MCE
CAS
1644248-18-9

DESCRIPTION [1644248-18-9]

Overview

MDL-
Molecular Weight339.34
Molecular FormulaC16H19F2N3O3
SMILESN[C@@H](C(NC1=CC=C(C(OC(F)F)=C1)C2=CN=CO2)=O)CC(C)C

For research use only. We do not sell to patients.

Summary

BMS-911172 is an adaptor associated kinase 1 (AAK1 kinase) inhibitor ( IC 50 = 35 nM).


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 294.69 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9469 mL 14.7345 mL 29.4690 mL
5 mM 0.5894 mL 2.9469 mL 5.8938 mL
10 mM 0.2947 mL 1.4734 mL 2.9469 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (7.37 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (7.37 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.