[CAS NO. 16754-80-6]  6-Chloro-7-deazapurine-β-D-riboside

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PRODUCTS SPECIFICATIONS [16754-80-6]

Catalog
HY-W054064
Brand
MCE
CAS
16754-80-6

DESCRIPTION [16754-80-6]

Overview

MDLMFCD03425528
Molecular Weight285.68
Molecular FormulaC11H12ClN3O4
SMILESO[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3Cl)=C3C=C2)O[C@@H]1CO

For research use only. We do not sell to patients.

Summary

Chloro-7-deazapurine-β-D-riboside is a nucleoside derivative and has antifungal activity [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, stored under nitrogen

* The compound is unstable in solutions, freshly prepared is recommended.


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 350.04 mM ; Need ultrasonic)

H 2 O : 4.35 mg/mL ( 15.23 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5004 mL 17.5021 mL 35.0042 mL
5 mM 0.7001 mL 3.5004 mL 7.0008 mL
10 mM 0.3500 mL 1.7502 mL 3.5004 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (8.75 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.75 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.75 mM); Clear solution

  • 4.

    Add each solvent one by one: PBS

    Solubility: 2 mg/mL (7.00 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

* All of the co-solvents are available by MCE.