[CAS NO. 1679-53-4] 10-Hydroxydecanoic acid

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PRODUCTS SPECIFICATIONS [1679-53-4]

Catalog

HY-Y0148

Brand

MCE

CAS

1679-53-4

DESCRIPTION [1679-53-4]

Overview

MDL	MFCD00010510
Molecular Weight	188.26
Molecular Formula	C10H20O3
SMILES	O=C(O)CCCCCCCCCO

For research use only. We do not sell to patients.

Summary

10-Hydroxydecanoic acid (NSC 15139) is a saturated fatty acid of 10-hydroxy-trans-2-decenoic acid from royal jelly, with anti-inflammatory activity ^[1] .

Appearance

Solid

Source

major fatty acids in royal jelly

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 265.59 mM ; Need ultrasonic)

H ₂ O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3118 mL	26.5590 mL	53.1180 mL
5 mM	1.0624 mL	5.3118 mL	10.6236 mL
10 mM	0.5312 mL	2.6559 mL	5.3118 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 1.25 mg/mL (6.64 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1.25 mg/mL (6.64 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1.25 mg/mL (6.64 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Takahashi K, et al. Inhibitory effect of 10-hydroxydecanoic acid on lipopolysaccharide-induced nitric oxide production via translational downregulation of interferon regulatory factor-1 in RAW264 murine macrophages. Biomed Res. 2013 Aug;34(4):205-14.

Synonyms

Decanoic acid, 10-hydroxy-

10-Hydroxydecanoic acid

NSC 15139