[CAS NO. 168161-71-5]  (Rac)-Sograzepide

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PRODUCTS SPECIFICATIONS [168161-71-5]

Catalog
HY-U00360
Brand
MCE
CAS
168161-71-5

DESCRIPTION [168161-71-5]

Overview

MDL-
Molecular Weight498.58
Molecular FormulaC28H30N6O3
SMILESO=C(NC1=CC=CC(NC)=C1)NC2C(N(CC(C(C)(C)C)=O)C3=CC=CC=C3C(C4=NC=CC=C4)=N2)=O

For research use only. We do not sell to patients.

Summary

(Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor , and has the potential of reducing the secretion of gastric acid.


IC50 & Target

CCK-B receptor [1]


In Vitro

(Rac)-Sograzepide is an antagonist of CCK-B receptor, and has the potential of reducing the secretion of gastric acid [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 250.71 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0057 mL 10.0285 mL 20.0570 mL
5 mM 0.4011 mL 2.0057 mL 4.0114 mL
10 mM 0.2006 mL 1.0028 mL 2.0057 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (4.17 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.17 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.17 mM); Clear solution

* All of the co-solvents are available by MCE.