[CAS NO. 17388-39-5] Swertiamarin

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PRODUCTS SPECIFICATIONS [17388-39-5]

Catalog

HY-N0807

Brand

MCE

CAS

17388-39-5

DESCRIPTION [17388-39-5]

Overview

MDL	MFCD07783984
Molecular Weight	374.34
Molecular Formula	C16H22O10
SMILES	C=C[C@@H]([C@@H]1O[C@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CO)[C@@](C3=CO1)(CCOC3=O)O

For research use only. We do not sell to patients.

Summary

Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma littorale , confers anti-hyperglycemic and anti-hyperlipidemic effects ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 667.84 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6714 mL	13.3568 mL	26.7137 mL
5 mM	0.5343 mL	2.6714 mL	5.3427 mL
10 mM	0.2671 mL	1.3357 mL	2.6714 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.17 mg/mL (5.80 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.17 mg/mL (5.80 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.17 mg/mL (5.80 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Patel N, et al. Curr Drug Targets. 2018;19(16):1958-1967. doi: 10.2174/1389450119666180406113428.

Synonyms

1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-6-(β-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-4a-hydroxy-, (4aR,5R,6S)-

Swertiamarin

1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-6-(β-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-4a-hydroxy-, [4aR-(4aα,5β,6α)]-

(4aR,5R,6S)-5-Ethenyl-6-(β-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-4a-hydroxy-1H,3H-pyrano[3,4-c]pyran-1-one

Swertiamarine

Swertiamaroside

Swertamarin

Swertimarin