[CAS NO. 174568-92-4]  GlyoxalaseIinhibitorfreebase

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PRODUCTS SPECIFICATIONS [174568-92-4]

Catalog
HY-15167A
Brand
MCE
CAS
174568-92-4

DESCRIPTION [174568-92-4]

Overview

MDL-
Molecular Weight577.45
Molecular FormulaC21H29BrN4O8S
SMILESN[C@H](C(OCC)=O)CCC(N[C@@H](CSC(N(O)C1=CC=C(Br)C=C1)=O)C(NCC(OCC)=O)=O)=O

For research use only. We do not sell to patients.


Summary

Glyoxalase I inhibitor (free base) is a potent Glyoxalase I (GLO1) inhibitor, candidate for anticancer agents.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 173.18 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7318 mL 8.6588 mL 17.3175 mL
5 mM 0.3464 mL 1.7318 mL 3.4635 mL
10 mM 0.1732 mL 0.8659 mL 1.7318 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.75 mg/mL (4.76 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.75 mg/mL (4.76 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.75 mg/mL (4.76 mM); Clear solution

* All of the co-solvents are available by MCE.