[CAS NO. 1777807-64-3] ZINC03129319
PRODUCTS SPECIFICATIONS [1777807-64-3]
DESCRIPTION [1777807-64-3]
Overview
| MDL | MFCD31657427 |
|---|---|
| Molecular Weight | 490.51 |
| Molecular Formula | C24H14N2O6S2 |
| SMILES | O=C1C2(SC[C@H]3N2C([C@@H]4N(C5(C(C(C=CC=C6)=C6C5=O)=O)SC4)C3=O)=O)C(C7=CC=CC=C71)=O |
Summary
ZINC03129319 is a dengue virus ( DENV ) NS2B-NS3 protease inhibitor extracted from patent US20150141521A1, has inhibition constants ( K i1 ) of 92 μM and K i3 of 20 μM.
In Vitro
ZINC03129319 inhibits DENV NS2B-NS3 protease with K i1 of 92±15 μM and K i3 of 20±4 μM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 41.67 mg/mL ( 84.95 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.0387 mL | 10.1935 mL | 20.3869 mL |
| 5 mM | 0.4077 mL | 2.0387 mL | 4.0774 mL |
| 10 mM | 0.2039 mL | 1.0193 mL | 2.0387 mL |
Synonyms