[CAS NO. 17833-53-3] N-Methyl-DL-aspartic acid
PRODUCTS SPECIFICATIONS [17833-53-3]
DESCRIPTION [17833-53-3]
Overview
| MDL | MFCD00065918 |
|---|---|
| Molecular Weight | 147.13 |
| Molecular Formula | C5H9NO4 |
| SMILES | O=C(O)CC(C(O)=O)NC |
Summary
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 16.67 mg/mL ( 113.30 mM ; Need ultrasonic)
DMSO : 4.17 mg/mL ( 28.34 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 6.7967 mL | 33.9836 mL | 67.9671 mL |
| 5 mM | 1.3593 mL | 6.7967 mL | 13.5934 mL |
| 10 mM | 0.6797 mL | 3.3984 mL | 6.7967 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 16.67 mg/mL (113.30 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 0.42 mg/mL (2.85 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 0.42 mg/mL (2.85 mM); Clear solution
References
- [1] G R Lauretti, et al. The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole. Neuropharmacology. 1994 Feb;33(2):155-60.
- [2] S J Czuczwar, et al. Antagonism of N-methyl-D,L-aspartic acid-induced convulsions by antiepileptic drugs and other agents. Eur J Pharmacol. 1985 Feb 5;108(3):273-80
Synonyms