[CAS NO. 1787787-60-3] NLRP3/AIM2-IN-3
PRODUCTS SPECIFICATIONS [1787787-60-3]
DESCRIPTION [1787787-60-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 266.29 |
| Molecular Formula | C16H14N2O2 |
| SMILES | O=C(NC1=CC=CC(O)=C1)CC2=CC3=C(C=C2)C=CN3 |
Summary
NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of < b > NLRP3 < / b > and < b > AIM2 < / b > inflammatory bodies and has species differences. Its < b > IC < sub > 50 < / sub > < / b > value is 0.077 ± 0.008 μ M。
IC50 & Target
|
inhibitory activity against NLRP3 and AIM2 0.077±0.00 μM (IC 50 ) |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 250 mg/mL ( 938.83 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.7553 mL | 18.7765 mL | 37.5530 mL |
| 5 mM | 0.7511 mL | 3.7553 mL | 7.5106 mL |
| 10 mM | 0.3755 mL | 1.8777 mL | 3.7553 mL |