[CAS NO. 1818885-63-0]  Pomalidomide-PEG4-Ph-NH2

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PRODUCTS SPECIFICATIONS [1818885-63-0]

Catalog
HY-41549
Brand
MCE
CAS
1818885-63-0

DESCRIPTION [1818885-63-0]

Overview

MDLMFCD30490723
Molecular Weight540.57
Molecular FormulaC27H32N4O8
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOC4=CC=C(N)C=C4)=O

For research use only. We do not sell to patients.

Summary

Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.


IC50 & Target

Cereblon


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL ( 92.49 mM )

H 2 O : < 0.1 mg/mL (insoluble)

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8499 mL 9.2495 mL 18.4990 mL
5 mM 0.3700 mL 1.8499 mL 3.6998 mL
10 mM 0.1850 mL 0.9249 mL 1.8499 mL
* Please refer to the solubility information to select the appropriate solvent.