[CAS NO. 18642-44-9]  Actein

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PRODUCTS SPECIFICATIONS [18642-44-9]

Catalog
HY-N6872
Brand
MCE
CAS
18642-44-9

DESCRIPTION [18642-44-9]

Overview

MDLMFCD25371991
Molecular Weight676.83
Molecular FormulaC37H56O11
SMILESC[C@]12[C@@]3([H])[C@@]4(C[C@@H](OC(C)=O)[C@@]1([C@]5([H])[C@](O[C@]6([C@H]7[C@]([C@@H](O)O6)(C)O7)C[C@H]5C)([H])C2)C)[C@@]8([C@@](C(C)([C@@H](O[C@@]9([H])[C@@H]([C@H]([C@H](O)CO9)O)O)CC8)C)([H])CC3)C4

For research use only. We do not sell to patients.

Summary

Actein is a triterpene glycoside isolated from the rhizomes of Cimicifuga foetida . Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in human bladder cancer . Actein has little toxicity in vivo [1] [2] .


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 147.75 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4775 mL 7.3874 mL 14.7748 mL
5 mM 0.2955 mL 1.4775 mL 2.9550 mL
10 mM 0.1477 mL 0.7387 mL 1.4775 mL
* Please refer to the solubility information to select the appropriate solvent.


Synonyms

β-D-Xylopyranoside, (3β,12β,16β,23R,24R,25S,26S)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-26-hydroxy-9,19-cyclolanostan-3-yl
Actein
Spiro[5H-cyclopropa[1′,8′a]naphth[2′,1′:4,5]indeno[2,1-b]pyran-10(2H),2′-[3,6]dioxabicyclo[3.1.0]hexane], β-D-xylopyranoside deriv.
9,19-Cyclolanostane, β-D-xylopyranoside deriv.
(3β,12β,16β,23R,24R,25S,26S)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-26-hydroxy-9,19-cyclolanostan-3-yl β-D-xylopyranoside
Shengmating