[CAS NO. 19083-00-2] Gracillin

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PRODUCTS SPECIFICATIONS [19083-00-2]

Catalog

HY-N0706

Brand

MCE

CAS

19083-00-2

DESCRIPTION [19083-00-2]

Overview

MDL	MFCD28978176
Molecular Weight	885.04
Molecular Formula	C45H72O17
SMILES	C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])C[C@@]1([H])[C@@](CC=C5[C@@]6(CC[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)([H])[C@@H]7O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)C5)C)([H])[C@]6([H])CC2

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Immunopharmacol Immunotoxicol. 2021 Oct 7;1-12.

Summary

Gracillin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica with antitumor agent. Gracillin could induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells.[1]

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 282.47 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1299 mL	5.6495 mL	11.2989 mL
5 mM	0.2260 mL	1.1299 mL	2.2598 mL
10 mM	0.1130 mL	0.5649 mL	1.1299 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (2.35 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Chen CR et al. Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1. Pharmazie. 2015 Mar;70(3):199-204.

Synonyms

β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-

Gracillin

(3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranoside

Diosgenin 3-O-β-gracillimatrioside

Gracilline

Lilioglycoside G

Diosgenin 3-O-(α-L-rhamnopyranosyl(1→2)-[β-D-glucopyranosyl(1→3)])-β-D-glucopyranoside

NSC 698787

25(R)-Diosgenin 3-O-β-D-glucopyranosyl-(1→3)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside

Dulcamarin C