[CAS NO. 1914971-16-6]  PHGDH-inactive

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PRODUCTS SPECIFICATIONS [1914971-16-6]

Catalog
HY-121733
Brand
MCE
CAS
1914971-16-6

DESCRIPTION [1914971-16-6]

Overview

MDL-
Molecular Weight327.45
Molecular FormulaC17H21N5S
SMILESS=C(NC1=NC(C)=CC(C)=C1)N2CCN(CC2)C3=CC=NC=C3

For research use only. We do not sell to patients.

Summary

PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503 [1] .


In Vitro

PHGDH-inactive has no activity against PHGDH and serves as a negative control [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 83.33 mg/mL ( 254.48 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0539 mL 15.2695 mL 30.5390 mL
5 mM 0.6108 mL 3.0539 mL 6.1078 mL
10 mM 0.3054 mL 1.5270 mL 3.0539 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (6.35 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (6.35 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.35 mM); Clear solution

* All of the co-solvents are available by MCE.