[CAS NO. 191729-43-8] Tenacissoside G

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PRODUCTS SPECIFICATIONS [191729-43-8]

Catalog

HY-N2103

Brand

MCE

CAS

191729-43-8

DESCRIPTION [191729-43-8]

Overview

MDL	-
Molecular Weight	792.95
Molecular Formula	C42H64O14
SMILES	C[C@@]([C@@H]([C@@H](OC(/C(C)=C/C)=O)[C@]1([H])[C@]23C)OC(C)=O)([C@@H]4C(C)=O)[C@]5(CC4)[C@@]1(CC[C@@]2([H])C[C@@H](O[C@@](O[C@H](C)[C@H]6O[C@@](O[C@H](C)[C@@H](O)[C@H]7OC)([H])[C@@H]7O)([H])C[C@H]6OC)CC3)O5

For research use only. We do not sell to patients.

Summary

Tenacissoside G is a C21 steroid from the stems of Marsdenia tenacissima . Tenacissoside G reverses multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells ^[1] ^[2] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 126.11 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2611 mL	6.3056 mL	12.6111 mL
5 mM	0.2522 mL	1.2611 mL	2.5222 mL
10 mM	0.1261 mL	0.6306 mL	1.2611 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (3.15 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (3.15 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (3.15 mM); Clear solution

* All of the co-solvents are available by MCE.