[CAS NO. 2052969-18-1] Upacicalcet sodium
PRODUCTS SPECIFICATIONS [2052969-18-1]
DESCRIPTION [2052969-18-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 373.75 |
| Molecular Formula | C11H13ClN3NaO6S |
| SMILES | O=C(NC[C@H](N)C(O[Na])=O)NC1=CC(S(=O)(O)=O)=CC(Cl)=C1C |
Summary
Upacicalcet sodium is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) [1] .
IC50 & Target
calcium-sensing receptors [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL ( 267.56 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.6756 mL | 13.3779 mL | 26.7559 mL |
| 5 mM | 0.5351 mL | 2.6756 mL | 5.3512 mL |
| 10 mM | 0.2676 mL | 1.3378 mL | 2.6756 mL |