[CAS NO. 20562-02-1] α-Solanine

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PRODUCTS SPECIFICATIONS [20562-02-1]

Catalog

HY-N6602

Brand

MCE

CAS

20562-02-1

DESCRIPTION [20562-02-1]

Overview

MDL	-
Molecular Weight	868.06
Molecular Formula	C45H73NO15
SMILES	C[C@@]12[C@]3([H])[C@](N4[C@@](CC[C@H](C)C4)([H])[C@H]3C)([H])C[C@@]1([H])[C@@]5([H])[C@]([C@@]6(C(C[C@@H](O[C@@]7([H])[C@@H]([C@H]([C@@H](O)[C@@H](CO)O7)O[C@]8([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)CO)O[C@@]9([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O9)O)O)CC6)=CC5)C)([H])CC2

For research use only. We do not sell to patients.

Summary

α-solanine, a bioactive component and one of the major steroidal glycoalkaloids in Solanum nigrum , has been observed to inhibit growth and induce apoptosis in cancer cells ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 57.60 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1520 mL	5.7600 mL	11.5199 mL
5 mM	0.2304 mL	1.1520 mL	2.3040 mL
10 mM	0.1152 mL	0.5760 mL	1.1520 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 1.25 mg/mL (1.44 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1.25 mg/mL (1.44 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1.25 mg/mL (1.44 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Lei Wang , et al. Inhibitory Effect of α-Solanine on Esophageal Carcinoma in vitro. Exp Ther Med. 2016 Sep;12(3):1525-1530.

Synonyms

β-D-Galactopyranoside, (3β)-solanid-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-

α-Solanine

Solanidane, β-D-galactopyranoside deriv.

1H-Naphth[2′,1′:4,5]indeno[1,2-b]indolizine, β-D-galactopyranoside deriv.

(3β)-Solanid-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranoside

α-Solanin